Originally designed to function in AR-type rifles, the 24 Nosler proves to be a capable hunting cartridge in other platforms, including the Nosler Custom Handgun. Steve Gash examines the cartridge’s design, compares its ballistic roots to other small-cased 6mm rounds, and tests a wide range of Hodgdon, IMR, and Winchester powders. His results show strong accuracy, excellent handloading flexibility, and standout performance from CFE 223, making the 24 Nosler a serious option for varmints, deer, antelope, and other medium-sized game.